Molecular mechanism behind autoimmune diseases found

"The development of Treg cells in the thymus depends on super-enhancer establishment," said Shimon Sakaguchi from Osaka University in Japan.
Understanding the development of Treg cells is thought to be critical for combating autoimmune diseases.

Scientists have discovered a new molecular mechanism behind some autoimmune diseases, an advance that may pave the way for new treatments against conditions caused by hyperactive immune systems.

While the immune system is crucial for protecting the body from infection and disease, prolonged activation can damage healthy tissue.

After its activation, the immune system is shut off by specialised immune cells known as regulatory T cells (Treg cells), researchers said. Full Story