Gene therapy may treat Alzheimer’s

Worldwide 47.5 million people are affected by dementia ? of which Alzheimers is the most common form, researchers said.
Amyloid-beta peptide is the main component of amyloid plaques, the sticky clumps of protein found in the brains of people with Alzheimers disease. These plaques are thought to trigger the death of brain cells.

Researchers at the Imperial College here have found that delivering a specific gene via an injection directly into the brain may offer a potential new therapy for halting the progress of Alzheimer’s disease, especially when treated in its early stages.

In the study, published in the journal Proceedings of the National Academy of Sciences, the team used a type of modified virus to deliver a gene to brain cells of mice.

“Although these findings are very early they suggest this gene therapy may have potential therapeutic use for patients,” said senior study author Magdalena Sastre. Full Story